Jinan Hongyuan Chemical Co.,Ltd

Jinan Hongyuan Chemical Co.,Ltd

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Jinan Hongyuan Chemical Co.,Ltd
Página inicialLista de ProdutoMatéria-prima QuímicaTintura IntermediáriaDroga bruta reguladora de lipídios Lovastatina 75330-75-5

Droga bruta reguladora de lipídios Lovastatina 75330-75-5

Tipo de pagamento:
L/C,T/T,D/P,Paypal,Money Gram,Western Union
Incoterm:
FOB,FCA,CIP
Quantidade de pedido mínimo:
1 Kilogram
transporte:
Ocean,Land,Air
porta:
Shanghai,Qingdao
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  • Descrição do produto
Overview
Atributos do produto

Modelo75330-75-5

marcaMingya

Capacidade de fornecimento e informaçõ...

Pacote25kg / Tambor

produtividade5000mt One Year

transporteOcean,Land,Air

Lugar de origemChina

Apoio sobre1000kg

Certificados state-owned enterprise

Código HS2932999099

portaShanghai,Qingdao

Tipo de pagamentoL/C,T/T,D/P,Paypal,Money Gram,Western Union

IncotermFOB,FCA,CIP

Embalagem & Entrega
Unidades de venda:
Kilogram
Tipo de pacote:
25kg / Tambor

Matéria-prima química Lovastatina CAS 75330-75-5

Purpose:

Lovastatin is a kind of HMG CoA reductase inhibitor which is used to reduce the cell permeability of cholesterol.
effect:
1. Lipid regulating effect
Lovastatin can block the synthesis of endogenous cholesterol by inhibiting HMG CoA reductase, which is the rate limiting enzyme of cholesterol synthesis. Lovastatin can reduce the content of cholesterol in cells, increase the number of LDL receptors on cell surface, accelerate the uptake and degradation of LDL particles in blood circulation, and reduce the total cholesterol, very low density lipoprotein (VLDL), LDL and triglyceride in plasma. Since the conversion of HMG CoA to mevalonate is an early step in cholesterol biosynthesis pathway, lovastatin does not lead to accumulation of potentially toxic cholesterol substances. HMG CoA can also be quickly reversed into acetyl coenzyme A and participate in other biosynthetic pathways in vivo. This inhibition is incomplete and reversible, and there is a dose-response relationship, Therefore, lovastatin has a significant effect on reducing blood lipid and has less side effects.
Generally speaking, lovastatin mainly plays a role in the following aspects: ① competitive inhibition of HMG CoA reductase activity and reduction of endogenous cholesterol synthesis; ② increase of LDL receptor expression in hepatocytes and increase receptor mediated plasma LDL clearance rate; ③ inhibit migration and proliferation of smooth muscle cells; ④ reduce assembly and secretion of liver lipoprotein.
2. Non lipid regulating effect
Lovastatin can not only significantly reduce blood lipid, but also significantly improve the function of endothelial cells, promote the production of nitric oxide synthase (eNOS), thus increasing the synthesis and release of no, which plays a key role in maintaining normal pulmonary vascular tension and reversing hypoxia induced pulmonary vasoconstriction and vascular remodeling. In addition, lovastatin has anti-inflammatory and antiproliferative effects, which can inhibit the proliferation of mesangial cells and the secretion of extracellular matrix, so as to reduce glomerulosclerosis.

English alias:

Antibiotic MB 530B
Altoprev
Rovacor
6a-Methylcompactin

Name:                     Lovastatin  

Cas No:

CAS 75330-75-5
MF: C24H36O5
Appearance:
White Powder
purity:
>99%
Brand Name:
Ming ya
Delivery time:
Within 1-3 days payment
Export Markets:
Global


 Lovastatin CAS 75330-75-5


 Lovastatin CAS 75330-75-5

 Lovastatin CAS 75330-75-5


Outras categorias de produtos:

1 、 Matéria-prima química

2 、 Químicos Finos

3 、 Droga bruta

4 、 Farmacêutico intermediário

5 、 Outros produtos químicos

Nossa empresa é um profissional envolvido no comércio de importação e exportação, existem mais de dez tipos de produtos, centenas de produtos, a variedade de produtos é muito rica, sempre insistimos no preço mais preferencial para fornecer produtos da melhor qualidade, mais detalhes do produto , entre em contato conosco.

Grupo de Produto : Matéria-prima Química > Tintura Intermediária

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Página inicialLista de ProdutoMatéria-prima QuímicaTintura IntermediáriaDroga bruta reguladora de lipídios Lovastatina 75330-75-5
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